Schedule for ECOL/CPH 409/509: Evolution of Infectious Disease (3 units)
| Date | Topic | Readings | Lecture notes/slides |
| T Aug. 26 | Hand out syllabus, introductions | ||
| R Aug. 28 | Course overview | Lecture 1: PowerPoint |
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| T Sep. 2 | A brief introduction to evolutionary thinking | 1. Stearns (1999) "Introducing evolutionary thinking" (handout) 2.http://www.literature.org/authors/darwin-charles/the-origin-of-species/ (Read the last chapter of Darwin’s Origin) |
Lecture 2: PowerPoint |
| R Sep. 4 | The central role of parasites in evolution | 1. Haldane (1949) "Disease and evolution" (pdf file) 2. Hamilton (pdf) |
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| T Sep. 9 | The central role of parasites in evolution | Lecture 3: PowerPoint |
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| R Sep. 11 | Trees and disease: molecular epidemiology | Baldauf, SL (2003) Phylogeny for the faint of heart: a tutorial Trends in Genetics 19: 345-351 (pdf file) | Lecture 4: PowerPoint |
| T Sep. 16 | Trees and disease: molecular epidemiology | ||
| R Sep.18 | |||
| T Sep. 23 | EXAM - Midterm 1 | ||
| R Sep. 25 | Exam Review | ||
| T Sep. 30 | Guest lecture: Felicia Goodrum - Herpes viruses and evolution | Lecture 5: PowerPoint |
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| R Oct. 2 | Case study: emergence of HIV | Worobey08 | Lecture 6: PowerPoint |
| T Oct. 7 | Film: "And the Band Played On" | ||
| R Oct. 9 | Film: "And the Band Played On" | ||
| T Oct. 14 | Immunology and disease: how vertebrate immunity works | Frank (2002) “Immunology and Infectious Disease” (chapters 1 - 5) | Lecture 7: PowerPoint |
| R Oct. 16 | Immunology and disease: how vertebrate immunity works | Bergstrom06 | Lecture 8: PowerPoint |
| T Oct. 21 | Immunology and disease: how vertebrate immunity works |
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| R Oct. 23 | Guest lecture: Joel Wertheim - Biodiversity of pathogens | Lecture 9: |
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| T Oct. 28 | Immunology and disease: antigenic variation of disease agents | Frank (2002) “Immunology and Infectious Disease” (chapter 5) |
Lecture 10: PowerPoint |
| R Oct. 30 | EXAM | ||
| T Nov. 4 | Exam Review | ||
| R Nov. 6 | Guest lecture: Joel Wertheim - Evolution of virulence | Ewald 1993 The Evolution of Virulence (pdf file) Levin 1996 The Evolution and Maintenance of Virulence in Microparasites (pdf file) Galvani 2003 Epidemiology Meets Evolutionary Ecology (pdf file) |
Lecture 11: PowerPoint |
| T Nov. 11 | Veterans Day - no class | ||
| R Nov. 13 | Control of infectious disease: antimicrobial resistance | Lecture 12: PowerPoint |
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| T Nov. 18 | Control of infectious disease: antimicrobial resistance (cont'd) | ||
| R Nov. 20 | Control of infectious disease: vaccines and evolution | Lecture 13: PowerPoint |
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| T Nov. 25 | Control of infectious disease: vaccines and evolution (cont'd) | ||
| R Nov. 27 | Thanksgiving: no class | ||
| T Dec. 2 | Graduate student presentations | ||
| R Dec. 4 | In class FINAL EXAM | ||
| T Dec. 9 | TERM PAPER DUE | ||